What symptoms may indicate an overdose on CNS depressants?

An overdose on CNS (central nervous system) depressants typically leads to symptoms that reflect the slowing down of bodily functions. Cold, clammy skin is a notable physiological response when someone is experiencing significant depression of the nervous system. This may occur because the body's systems are becoming less responsive, leading to reduced circulation and compromised temperature regulation.

In cases of overdose, the body's ability to maintain normal physiological responses can be impaired, resulting in skin that is not only cold but also clammy due to potential perspiration or other reactions to the body's stress response. These symptoms can also indicate a dangerously low blood pressure and a decreased level of consciousness, complicating the clinical picture.

The other symptoms listed, such as excessive energy, rapid pulse, and warm skin, do not align with typical manifestations of CNS depressant overdose. Excessive energy suggests stimulation, which is contrary to the nature of depressant effects. A rapid pulse and warm skin could indicate other medical conditions or responses but are not characteristic of CNS depressant overdoses, where the body's functions generally slow down.