What is a known side effect of high doses of dissociative anesthetics?

High doses of dissociative anesthetics, such as ketamine and phencyclidine (PCP), are known to cause various psychoactive effects, one of which can include aggressive behavior. This occurs as these substances impact the brain's neurotransmitter systems, particularly those involved in mood regulation and perception. When dissociative anesthetics are consumed in large quantities, they can produce dissociative states, altered perceptions of reality, and heightened emotional responses, which may manifest as aggression in some individuals.

The other options listed, such as sudden weight loss, increased vision acuity, and allergy to medications, do not align with the recognized effects of high-dosage dissociative anesthetics. Weight loss is not a typical side effect associated with their use, nor is there a direct correlation between these substances and improvements in vision acuity. Allergic reactions to medications generally relate to immune responses, which are not specifically linked to the acute effects of dissociative anesthetics. Therefore, aggressive behavior stands out as a well-documented side effect in cases of high doses.