What condition is typically indicated by chronic fatigue, paranoia, and psychosis?

Chronic fatigue, paranoia, and psychosis can often be associated with cannabis abuse. When someone abuses cannabis, they might experience heightened anxiety and a distorted perception of reality, which can lead to paranoia and psychotic symptoms. The prolonged use at high levels can disrupt normal cognitive functions, contributing to confusion and fatigue.

While cannabis withdrawal might cause symptoms like irritability or sleep disturbances, it is not typically associated with paranoia and psychosis to the same degree. Cannabis tolerance refers to needing larger amounts of the substance to achieve the same effects but does not encompass the mental health issues described. Cannabis dependence is characterized by a compulsive use and withdrawal symptoms when not using; however, the specific symptoms of chronic fatigue, paranoia, and psychosis are more closely linked to the active, detrimental patterns seen in cannabis abuse rather than mere dependence.

In summary, cannabis abuse is the most accurate choice here as it encompasses the combination of serious psychological symptoms described in the question.